![]() ![]() Drainage from column heater Wash solvent direct from solvent bottle Mobile phase from solvent manager Sample Inject valve To column Degassed solvent from solvent manager Sample syringe valve Secondary drainage to solvent manager Secondary drainage to solvent manager Primary drainage to solvent manager Primary drainage to solvent manager 2ħ SM-FTN major components The following diagrams show the SM-FTN s major components. Flow path through the sample management system The following diagram shows how the SM-FTN functions as part of the ACQUITY UPLC system. See also: Column Compartments Operator's Overview and Maintenance Information on the ACQUITY UPLC System Documentation CD to avoid potential leaks or carryover. Use care when installing and removing reusable fittings. Ensure the drip tray does not collide with any surface. Bottle tray Detector Column heater Sample Manager - Flow Through Needle Solvent manager Overview 1Ħ Tips: Use care when stacking or moving the SM-FTN. Location of SM-FTN in the ACQUITY UPLC system The following diagram shows the location of the SM-FTN in the ACQUITY UPLC system. Using the SM-FTN, you also can dilute injected samples (auto-dilution). Optional extension loops (installed between the sample needle and the injection valve) increase the volume of your injections beyond that of the sample needle. Using a flow-through-needle mechanism, in which the needle is part of the high-pressure sample flow path, the Sample Manager injects the samples it draws from the plates and vials onto a chromatographic column. 7 Preparing for operation Installing the leak sensor Installing the waste tubing Calibrating the needle s z axis Priming the SM-FTN Using the SM-FTN Interface requirements Installation recommendations for fittings Selecting purge and wash solvents Washing the SM-FTN needle Loading sample plates Sample chamber considerations Choosing needles and extension loops Choosing the sample syringe Choosing the sample syringe draw rate Choosing the needle height setting Recovering maximum sample from vials Revising a plate type Air gaps Load-ahead and loop offline options Auto additions Auto dilution Diagnostic tests Resolving leak sensor errors Table of Contents iiiĤ Maintaining the SM-FTN Contacting Waters technical service Maintenance schedule Maintenance considerations Configuring maintenance warnings Replacing the leak sensor Replacing the seal Replacing the sample needle and needle guide Replacing the sample syringe Cleaning the injection port Replacing the injection valve cartridge Cleaning the instrument s exterior iv Table of Contentsĥ Overview You can submit samples for analysis on the ACQUITY UPLC system by loading microtiter plates or vials onto the rotary sample tray of the Sample Manager-Flow Through Needle (SM-FTN). 1 Flow path through the sample management system. 1 Location of SM-FTN in the ACQUITY UPLC system. In no event shall Waters Corporation be liable for incidental or consequential damages in connection with, or arising from, its use. This document is believed to be complete and accurate at the time of publication. Waters Corporation assumes no responsibility for any errors that may appear in this document. The information in this document is subject to change without notice and should not be construed as a commitment by Waters Corporation. THIS DOCUMENT OR PARTS THEREOF MAY NOT BE REPRODUCED IN ANY FORM WITHOUT THE WRITTEN PERMISSION OF THE PUBLISHER. ![]() PRINTED IN THE UNITED STATES OF AMERICA AND IN IRELAND. 1 ACQUITY UPLC Sample Manager - Flow Through Needle Operator s Overview and Maintenance Information Revision C Copyright Waters Corporation All rights reservedĢ Copyright notice WATERS CORPORATION. ![]()
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